翻訳と辞書 Words near each other ・ Return of results ・ Return of Sabata ・ Return of Saturn ・ Return of Sergeant Lapins ・ Return of service ・ Return of Shanghai Joe ・ Return of spontaneous circulation ・ Retrotransposon marker ・ Retrotronics ・ RetroUI ・ Retroversion of the sovereignty to the people ・ Retroverted uterus ・ Retroviral aspartyl protease ・ Retroviral matrix protein ・ Retroviral Psi packaging element ・ Retroviral ribonuclease H ・ Retrovirology (journal) ・ Retrovirus ・ Retrovirus direct repeat 1 (dr1) ・ Retrovirus RTS ・ Retrovisceral space ・ Retrovision ・ Retry ・ Retráctate ・ RETSAT ・ Retschenbach ・ Retschow ・ Retschwil ・ Retschwiller ・ RETScreen Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Retroviral ribonuclease H ： ウィキペディア英語版 Retroviral ribonuclease H The retroviral ribonuclease H (retroviral RNase H) is a catalytic domain of the retroviral reverse transcriptase (RT) enzyme. The RT enzyme is used to generate complementary DNA (cDNA) from the retroviral RNA genome. This process is called reverse transcription. To complete this complex process, the retroviral RT enzymes need to adopt a multifunctional nature. They therefore possess 3 of the following biochemical activities: RNA-dependent DNA polymerase, ribonuclease H, and DNA-dependent DNA polymerase activities ). Like all RNase H enzymes, the retroviral RNase H domain cleaves DNA/RNA duplexes and will not degrade DNA or unhybridized RNA. ==Structure== Although the RT structures from human, murine and avian retroviruses display different subunits, the relative sizes, orientation and connection of the DNA polymerase and RNase H domains are strikingly similar. The RNase H domain occupies ~25% of the RT protein C-terminal. The DNA polymerase domain occupies ~55% of the RT protein N-terminal. The RNase H domains of MMLV and HIV-1 RT enzymes are structural very similar to the Escherichia coli and Bacillus halodurans RNases H as well as to human RNaseH1. In general, the folded structures of retroviral RNase H domains take the form of 5-stranded mixed beta sheets flanked by four alpha helices in an asymmetric distribution. A notable difference between the various RNase H proteins is the presence or absence of the C-helix (present in E. coli, MLV and human RNases H, absent in HIV-1, B. halodurans and ASLV RNases H), a positively charged alpha helix also referred to as the basic loop or protrusion. It is believed to have a role in substrate binding. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Retroviral ribonuclease H」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.